PhD-Student Development of microchip NMR detection - University of Twente
PhD-Student Development of microchip NMR detection |
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TheFaculty of Science at the Radboud University in Nijmegen (TheNetherlands) provides Bachelor and Master education in Physics,Chemistry, Biology, Mathematics, Computational Science andEnvironmental Science. The Institute for Molecules and Materials (IMM,formerly known as NSRIM) conducts research at the interface of physicsand chemistry. It is focused on the design, synthesis and study of theproperties of molecules (including biomolecules) and materials. The IMMhouses a number of national and international facilities, including alarge scale NMR facility with instruments up to 800 MHz.
TheUniversity of Twente is an entrepreneurial research university,offering education and research in areas ranging from public policystudies and applied physics to biomedical technology. The MESA+institute for nanotechnology, is the largest research institute of theUniversity of Twente. The institute trains graduate students andPhD-students and conducts research in the fields of nanotechnology,microsystems, materials science and microelectronics. The MESA+institute provides state of the art infrastructure and researchfacilities for micromachining and lithography.
Thecombined MESA+ and IMM institutes have a vacancy for a PhD positionaimed at the development of microchip NMR detection. This method willbe implemented as an analytical tool to follow chemical reactions in anon-chip reaction chamber. It is part of a collaborative project withinthe national Process On A Chip (POAC) program, sponsored by variousIndustries and the Ministry of Economic Affairs.
Inthe future there will be an increasing convergence of micro- andnanotechnologies with physics, chemistry and life sciences to improvethe quality of life. Nuclear magnetic resonance (NMR) plays animportant role in the structural analysis of molecular systems both inthe liquid and solid state. Because of the small magnetic moment ofnuclear spins one generally needs macroscopic amounts of sample toobtain a good signal to noise ratio in a limited time of measurement,however. Currently studies of chemical reactions, development ofsensors etc. are pursued in microfluidic environments. Such studies areimpossible without adequate analytical tools. It is the goal of thisproject to incorporate the most powerful analysis method (NMR) using anon-chip microcoil probe. The research is aimed at optimizing thesensitivity and resolution of this type of microcoil detection methods.Preliminary investigations have shown that this goal can be reachedusing innovative designs. These methods are implemented into aversatile setup that will be used to demonstrate the potential of thiskind of research. In the project we will investigate various novelschemes to enhance the sensitivity, response time and throughput of themicro-NMR system. As an option we will investigate the possibility todevelop a tabletop system that can be used in both research andindustry.
Weare looking for an enthusiastic researcher with a Master's degree inphysics or physical chemistry, and with adequate theoretical andexperimental skills. We prefer candidates with a good team spirit, wholike to work in an internationally oriented environment and are able tocollaborate with our partner groups on the crossroads between chemistryand (technical) physics.
The contract is for four years and is expected to lead to a PhD thesis. Monthly salary maximum € 2.283,00.
Furtherinformation about this position can be obtained from Prof.dr. A.P.M.Kentgens (e-mail A.Kentgens@science.ru.nl /http://www.solmr.science.ru.nl/, phone +31 24 3652078/3652004), or fromdr. J.G.E. Gardeniers (email j.g.e.gardeniers@utwente.nl / www.bios.el.utwente.nl phone +31 53 4894356).
Writtenapplications, including curriculum vitae, summary of research interestand experience, should be directed to Dr. J.G.E. Gardeniers, BIOSLab-on-a-Chip Group, University of Twente, Faculty of ElectricalEngineering, Mathematics and Computer Science, P.O. Box 217, 7500 AEEnschede, The Netherlands (email: j.g.e.gardeniers@utwente.nl). Vacancy number 05/002.
URL link : PhD-Student Development of microchip NMR detection - University of Twente
