An MRC-funded 3-year POSTDOCTORAL position is availableIMMEDIATELY to study a panel of pathogen-derivedperoxidases from Mycobacterium tuberculosis and Trypanosomacruzi with potential therapeutic targeting. Using anintegrated approach that combines NMR spectroscopy, X-raycrystallography, site-directed mutagenesis andbioinformatics we aim to relate the structure and functionof these enzymes and to provide the basis for thedevelopment of peroxidase-specific and pathogen-selectiveinhibitors.

We are looking for a dynamic and highly motivatedpost-doctoral research assistant with previous training inX-ray crystallography or NMR methods and structuralbiology. The PDRA will have to be able to handle multipleaspects of the structure characterisation and to havesignificant understanding of enzymology and thus it will beexpected that the candidate will have prior post-doctoralexperience in a relevant research field. The project willalso involve generation of various protein expressionconstructs and routine protein purification and this workwill be carried out in collaboration with a current PhDstudent.

The starting salary will start at Point 8 on the RAIAscale (£23,643 plus £2,330 London Allowance).

Applications including a CV and the names of tworeferees should be sent to

Dr Snezana Djordjevic,
Department of Biochemistry & Molecular Biology,
University College London,
Gower Street,
LondonWC1E 6BT.

For an informal discussion about the postplease contact either Dr Snezana Djordjevic (snezana@biochem.ucl.ac.uk)or Professor Paul Driscoll (p.driscoll@ucl.ac.uk).

UCL Taking Action for Equality

The closing date for applications is Friday 8th July2005.

Source: Postdoctoral Position in Structural Biology, University College London