FACULTY OF MEDICAL AND HUMAN SCIENCES DIVISION OF HUMAN DEVELOPMENT
CENTRE FOR MOLECULAR MEDICINE AND ACADEMIC UNIT OF MEDICAL GENETICS
POST-DOCTORAL RESEARCH ASSOCIATE (REF - MHS/196/05)

Youwill be required to study the relationship between fibulin-5 and theeye disease age related macular degeneration. The project, funded bythe Wellcome Trust, is to investigate the molecular mechanisms andconsequences of missense mutations in fibulin-5 associated with thisvery common cause of blindness in the elderly. The work will involveexpressing mutant proteins and investigating secretion, proteininteractions, cell adhesion, protein folding etc.

Youwill have a degree in Biological Sciences, together with a PhD inMolecular Biology or Molecular Genetics. In addition, you will havegood organisational and communication skills, including writtencommunication skills evidenced by presentations at scientific meetingsand publications in peer-reviewed journals. Experience of working withextracellular matrix proteins would be an advantage.

Funding is available for three years.

Salary:
range £21,640 - £29,128 p.a.

Informal enquiries:
Professor Dorothy Trump
Tel: 0161-276-1782; email: Dorothy.trump@manchester.ac.uk

The following are available in pdf format:
Further particulars - ref MHS/196/05
Application form (also in RTF format)
For further information on the University see www.manchester.ac.uk/  

Application forms and further particulars are also available from:
The Directorate of Human Resources
Chisholm Building
University of Manchester ,
Oxford Road
Manchester
M13 9PL

Tel: ++44 (0) 161 275 8835
Email: Mhs-hr@manchester.ac.uk

Please quote reference:
MHS/196/05

Closing date:
23 June 2005

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