Postdoctoral Position in Mammary Gland Development and Signaling at the University of Toronto, Canada

One or possibly two postdoctoral positions are available to study development of the embryonic and postnatal mammary gland. The lab is on the main campus of the University of Toronto and the PI is Dr. Paul Hamel.

These positions will be for one year with a possible extension for another year.

Individuals will study the role of the Hedgehog (Hh)-signaling pathway or the Wnt-signaling pathway in directing development and morphogenesis of the mammary gland during embryogenesis or in the postnatal animal. These projects employ a combination of genetic approaches, using a number of transgenic and knock-out animals, as well as molecular and cellular approaches. Signal transduction pathways regulated by the Hh-ligands or the Wnt-signaling pathway will be determined and their role in directing cell fate in the developing mammary gland determined. Novel interactions between components of the Hh-pathway and other signaling pathways, such as the ras pathway and estrogen-signaling pathway, will also be studied.

Applicants must have a Ph.D. in biomedical or biological sciences as well as demonstrated experience in molecular and cellular biology. Previous experience with mice, including surgery, would be an asset. Interested applicant should send a CV with a brief research statement as well as a list of references to paul[dot]hamel[at]utoronto[dot]ca